Description

2-(Trifluoromethyl)-5-Pyrimidineacetic Acid CAS NO 1216002-39-9 is a high-value, fluorinated pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a trifluoromethyl group and a carboxylic acid functionality, makes it an essential intermediate for creating compounds with enhanced biological activity and physicochemical properties. This product is primarily targeted at research and development teams in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve metabolic stability and bioavailability.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials that require fluorinated aromatic components.
• Chemical Biology & Proteomics: Employed as a versatile scaffold or linker molecule for creating chemical probes, enzyme inhibitors, and bioconjugates.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-(Trifluoromethyl)-5-Pyrimidineacetic Acid
CAS No.	1216002-39-9
Molecular Formula	C7H5F3N2O2
Molecular Weight	206.12 g/mol
Synonyms	5-Pyrimidineacetic acid, 2-(trifluoromethyl)-; 2-(Trifluoromethyl)pyrimidine-5-acetic acid; (2-(Trifluoromethyl)pyrimidin-5-yl)acetic acid; 1216002-39-9; 2-Trifluoromethyl-5-pyrimidine acetic acid; 5-Carboxymethyl-2-trifluoromethylpyrimidine
EINECS	Contact for details

Quality Control

Every batch of 2-(Trifluoromethyl)-5-Pyrimidineacetic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with a detailed Certificate of Analysis (COA) that includes results from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its acidic nature, keep away from strong bases, oxidizing agents, and incompatible materials. The container must be kept tightly sealed to protect the contents from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.