Description

4-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine-2-Carboxylic Acid is a high-purity heterocyclic building block of significant importance in modern pharmaceutical research and development. This compound serves as a critical synthetic intermediate for the creation of novel, targeted therapeutics. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of kinase inhibitors and other small molecule drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization campaigns due to its versatile pyrrolopyrimidine scaffold.
• Process Chemistry: Serves as a starting material or advanced intermediate in the scale-up and commercial route development for active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed in the development of chemical probes and tool compounds for studying specific biological pathways and target validation.
• Custom Synthesis: A foundational block for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	4-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine-2-Carboxylic Acid
CAS No.	1215898-04-6
Molecular Formula	C7H4ClN3O2
Molecular Weight	197.58 g/mol
Synonyms	4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-2-carboxylic acid; 2-Pyrrolo[2,3-d]pyrimidinecarboxylic acid, 4-chloro-7H-; 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-2-carboxylate; 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-2-carboxylic acid (CAS 1215898-04-6); 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-2-carboxylic acid, 95+%; 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-2-carboxylic acid, 98+%; 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-2-carboxylic acid, Pharma Grade
EINECS	Contact for details

Quality Control

Our 4-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each lot, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.