Description

5-Bromo-2-Butoxypyrimidine is a high-purity pyrimidine derivative, a crucial halogenated heterocyclic building block in advanced organic synthesis. Its core value lies in enabling the precise construction of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce bromine and alkoxy functionalities into pyrimidine-based scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for creating functionalized organic materials, such as liquid crystals and organic semiconductors.
• Cross-Coupling Reactions: Acts as a versatile substrate in palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination for C-C and C-N bond formation.
• Chemical Biology Probes: Utilized in the development of molecular probes and labeled compounds for biochemical and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Bromo-2-Butoxypyrimidine
CAS No.	1215206-57-7
Molecular Formula	C8H11BrN2O
Molecular Weight	231.09 g/mol
Synonyms	2-Butoxy-5-bromopyrimidine; 5-Bromo-2-n-butoxypyrimidine; Pyrimidine, 5-bromo-2-butoxy-; 5-Bromo-2-butoxypyrimidine; 1215206-57-7; 5-Bromo-2-(butoxy)pyrimidine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Butoxypyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.