Description

4-Fluoro-n-Methyl-2-(Trifluoromethyl)Aniline Hydrochloride is a high-purity, fluorinated aniline derivative salt, serving as a critical building block in advanced organic synthesis. Its value lies in the unique combination of fluorine and trifluoromethyl groups, which are essential for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients, particularly in the development of new drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Material Science Research: Employed as a monomer or precursor for synthesizing specialty polymers, liquid crystals, and organic electronic materials with tailored properties.
• Chemical Biology & Proteomics: Acts as a versatile reagent for labeling and modifying biomolecules, facilitating drug discovery and diagnostic assay development.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scaled-up production under cGMP conditions for clinical trials and commercial supply.

Basic Information

Product Name	4-Fluoro-n-Methyl-2-(Trifluoromethyl)Aniline Hydrochloride
CAS No.	1215205-13-2
Molecular Formula	C9H8ClF4N
Molecular Weight	241.61 g/mol
Synonyms	4-Fluoro-N-methyl-2-(trifluoromethyl)aniline hydrochloride; 2-(Trifluoromethyl)-4-fluoro-N-methylaniline hydrochloride; 4-Fluoro-N,2-bis(trifluoromethyl)aniline hydrochloride (incorrect but common misnomer); 4-Fluoro-2-trifluoromethyl-N-methylaniline HCl; Benzenamine, 4-fluoro-N-methyl-2-(trifluoromethyl)-, hydrochloride; 1215205-13-2; FC-0347 (Potential research code)
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-n-Methyl-2-(Trifluoromethyl)Aniline Hydrochloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Production can be aligned with ISO 9001 standards, and development-scale batches are available for regulatory filing support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.