Description

n-Fmoc-Rs-2-Aminoadipic Acid 6-(1,1-Dimethylethyl) Ester is a high-purity, protected amino acid derivative essential for advanced peptide synthesis. This compound is a critical building block for researchers and manufacturers developing novel peptide-based pharmaceuticals and biochemical tools. It is primarily utilized in solid-phase peptide synthesis (SPPS) by pharmaceutical R&D, biotechnology, and fine chemical synthesis sectors to create complex peptide sequences with precise stereochemistry.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key Fmoc-protected intermediate for the controlled elongation of peptide chains, particularly those requiring the (R)-2-aminoadipic acid moiety.
• Pharmaceutical Research & Development: Used in the discovery and development of peptide therapeutics, hormones, and enzyme inhibitors.
• Bioconjugation: Serves as a modified amino acid for creating site-specifically labeled peptides for diagnostic and imaging applications.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to identify new bioactive compounds.
• Academic Research: A valuable reagent for studying peptide structure-activity relationships and protein engineering.
• Production of Custom Peptides: Used by CROs and CDMOs for the contract manufacturing of complex, non-standard peptides for clients.

Basic Information

Product Name	n-Fmoc-Rs-2-Aminoadipic Acid 6-(1,1-Dimethylethyl) Ester
CAS No.	1214886-49-3
Molecular Formula	C25H29NO6
Molecular Weight	439.50 g/mol
Synonyms	Fmoc-(R)-2-Aminoadipic acid 6-tert-butyl ester; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-aminohexanedioic acid 6-(1,1-dimethylethyl) ester; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)hexanedioic acid 6-tert-butyl ester; Fmoc-R-2-Aad(OtBu)-OH; Fmoc-D-2-Aminoadipic acid 6-tert-butyl ester; tert-Butyl (R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)hexanedioate
EINECS	Contact for details

Quality Control

Our n-Fmoc-Rs-2-Aminoadipic Acid 6-(1,1-Dimethylethyl) Ester is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for sensitive pharmaceutical research. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.