Description

5-Fluoro-2-(Difluoromethyl)Phenol is a versatile fluorinated phenolic intermediate of significant importance in advanced organic synthesis. Its unique structure, featuring both fluorine and a difluoromethyl group on the aromatic ring, makes it a valuable building block for creating complex molecules with tailored properties. This compound is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atoms can enhance biological activity, metabolic stability, and environmental profile.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance display technologies.
• Polymer Modification: Acts as a monomer or additive to introduce fluorine into polymer backbones, improving chemical resistance, thermal stability, and surface properties.
• Organic Electronic Materials: Employed in the development of materials for organic light-emitting diodes (OLEDs) and semiconductors due to its electron-withdrawing characteristics.
• Chemical Research & Development: A valuable reagent for exploring new fluorination reactions and constructing complex aromatic systems in academic and industrial R&D settings.

Basic Information

Product Name	5-Fluoro-2-(Difluoromethyl)Phenol
CAS No.	1214367-26-6
Molecular Formula	C7H5F3O
Molecular Weight	162.11 g/mol
Synonyms	2-(Difluoromethyl)-5-fluorophenol; 5-Fluoro-2-(difluoromethyl)phenol; Phenol, 5-fluoro-2-(difluoromethyl)-; 5-Fluoro-α,α-difluoro-o-cresol
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-(Difluoromethyl)Phenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.