Description

2,4-Dichloro-5-(Pyridin-3-Yl)Pyrimidine is a high-value heterocyclic building block of significant importance in modern pharmaceutical and agrochemical research. This compound serves as a versatile intermediate for the synthesis of more complex molecules, particularly in the development of kinase inhibitors and other biologically active agents. It is primarily sought after by research institutions, custom synthesis houses, and manufacturers in the life sciences sector for creating novel therapeutic candidates and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, leveraging its pyrimidine core structure.
• Chemical Biology Probes: Employed in the design and construction of molecular probes for studying enzyme function and signal transduction pathways.
• Material Science Research: Serves as a building block for creating organic electronic materials and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing APIs (Active Pharmaceutical Ingredients) for clinical trials.
• Academic & Industrial R&D: Fundamental research compound in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	2,4-Dichloro-5-(Pyridin-3-Yl)Pyrimidine
CAS No.	1214359-45-1
Molecular Formula	C9H5Cl2N3
Molecular Weight	226.06 g/mol
Synonyms	5-(3-Pyridinyl)-2,4-dichloropyrimidine; 2,4-Dichloro-5-(3-pyridyl)pyrimidine; 3-(2,4-Dichloropyrimidin-5-yl)pyridine; Pyrimidine, 2,4-dichloro-5-(3-pyridinyl)-; 2,4-Dichloro-5-pyridin-3-yl-pyrimidine
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-5-(Pyridin-3-Yl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production standards. Specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.