Description

2-Bromo-6-(Trifluoromethyl)Benzyl Alcohol is a versatile and high-value fluorinated aromatic building block. This compound is critical for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its unique trifluoromethyl and bromo substituents enable precise modulation of biological activity and physicochemical properties. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides, where the CF3 group enhances lipophilicity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated liquid crystals, polymers, and organic electronic materials.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for Suzuki, Sonogashira, and Buchwald-Hartwig amination reactions.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems.

Basic Information

Product Name	2-Bromo-6-(Trifluoromethyl)Benzyl Alcohol
CAS No.	1214350-24-9
Molecular Formula	C8H6BrF3O
Molecular Weight	255.04 g/mol
Synonyms	[2-Bromo-6-(trifluoromethyl)phenyl]methanol; 1-(Bromomethyl)-2-(trifluoromethyl)benzene-3-ol; 2-Bromo-α-(trifluoromethyl)benzyl alcohol; (2-Bromo-6-(trifluoromethyl)phenyl)methanol; 2-Bromo-6-trifluoromethylbenzyl alcohol; 2-Bromo-α,α,α-trifluoro-o-tolyl alcohol
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-(Trifluoromethyl)Benzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent oxidation or moisture uptake. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.5%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.