Description

(2-Bromo-3-(Trifluoromethyl)Phenyl)Methanamine Hydrochloride is a high-purity, halogenated benzylamine derivative, offered as a stable hydrochloride salt for enhanced handling and storage. This compound is a critical pharmaceutical intermediate and organic building block, valued for its unique trifluoromethyl and bromine substituents which are pivotal in modulating the biological activity and physicochemical properties of target molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Ligand and Catalyst Development: Used in organometallic chemistry and catalysis research to develop new ligands for transition metal complexes.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials due to its aromatic and halogenated structure.
• Chemical Biology Probes: Acts as a precursor for fluorescent tags or affinity probes used in biochemical and cellular studies.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP guidelines.

Basic Information

Product Name	(2-Bromo-3-(Trifluoromethyl)Phenyl)Methanamine Hydrochloride
CAS No.	1214339-18-0
Molecular Formula	C8H8BrClF3N
Molecular Weight	290.51 g/mol
Synonyms	1-(2-Bromo-3-(trifluoromethyl)phenyl)methanamine hydrochloride; [2-Bromo-3-(trifluoromethyl)phenyl]methanamine HCl; 2-Bromo-3-(trifluoromethyl)benzylamine hydrochloride; α-Amino-2-bromo-3-(trifluoromethyl)toluene hydrochloride; (2-Bromo-α,α,α-trifluoro-m-tolyl)methylamine hydrochloride; 1-(2-Bromo-3-(trifluoromethyl)phenyl)-N-methylmethanamine hydrochloride (common salt form); Benzenemethanamine, 2-bromo-3-(trifluoromethyl)-, hydrochloride
EINECS	Contact for details

Quality Control

Our (2-Bromo-3-(Trifluoromethyl)Phenyl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can be aligned with cGMP standards for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.