Description

2-Fluoro-5-Methoxybenzene-1-Sulfonyl Chloride is a high-purity, multi-functional chemical building block essential for advanced organic synthesis. This compound serves as a critical reagent for introducing the sulfonyl chloride functional group, enabling the creation of sulfonamides and sulfonate esters. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing potential drug candidates, particularly in the development of sulfonamide-based therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides.
• Material Science Research: Employed in the creation of specialized polymers and functional materials requiring sulfonyl linkages.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation and labeling of biomolecules.
• Custom Synthesis & Contract Manufacturing: A vital reagent for CROs and CDMOs producing bespoke compounds for client projects.
• Academic Research: Facilitates methodological development and exploration of new reaction pathways in university and institutional laboratories.

Basic Information

Product Name	2-Fluoro-5-Methoxybenzene-1-Sulfonyl Chloride
CAS No.	1214334-01-6
Molecular Formula	C7H6ClFO3S
Molecular Weight	224.64 g/mol
Synonyms	2-Fluoro-5-methoxybenzenesulfonyl chloride; 1-Fluoro-4-methoxy-2-sulfonylchloridobenzene; 5-Methoxy-2-fluorobenzenesulfonyl chloride; 2-Fluoro-5-methoxybenzene sulfonyl chloride; 2-Fluoroanisole-5-sulfonyl chloride; 2-Fluoro-5-methoxy phenylsulfonyl chloride; (2-Fluoro-5-methoxyphenyl)sulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-Methoxybenzene-1-Sulfonyl Chloride is produced and tested under strict quality management protocols. We ensure compliance with relevant industry standards for research and fine chemical intermediates. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.