Description

4-Fluoro-2-(Difluoromethyl)Phenol is a fluorinated phenolic compound that serves as a versatile and valuable building block in advanced organic synthesis. Its unique structure, featuring both fluorine atoms and a phenolic hydroxyl group, makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This high-purity intermediate is essential for research and production in pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorinated motifs for enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides where the difluoromethylphenol moiety contributes to efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor for fluorinated mesogens used in display technologies, improving dielectric anisotropy and thermal stability.
• Polymer Modification: Acts as a monomer or functionalizing agent for engineering plastics and high-performance polymers to impart specific chemical resistance or surface properties.
• Organic Electronic Materials: Employed in the synthesis of charge-transport materials and emitters for OLED (Organic Light-Emitting Diode) applications.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry research programs exploring structure-activity relationships (SAR).

Basic Information

Item	Detail
Product Name	4-Fluoro-2-(Difluoromethyl)Phenol
CAS No.	1214326-61-0
Molecular Formula	C7H5F3O
Molecular Weight	162.11 g/mol
Synonyms	2-(Difluoromethyl)-4-fluorophenol; 4-Fluoro-2-(difluoromethyl)phenol; 4-Fluoro-α,α-difluoro-o-cresol; Phenol, 4-fluoro-2-(difluoromethyl)-; (Difluoromethyl)-4-fluorophenol
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-(Difluoromethyl)Phenol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliable batch-to-batch consistency for your sensitive synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container must be kept tightly closed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.