Description

(R)-(5-Bromo-2-Fluorophenyl)(Cyclopropyl)Methanamine is a high-purity chiral amine building block of significant interest in advanced organic synthesis. Its core value lies in its unique stereochemistry and functional group arrangement, enabling the construction of complex, biologically active molecules with precise three-dimensional control. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating novel active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potential drug candidates, especially for central nervous system (CNS) targets and enzyme inhibitors.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where its fluorinated and brominated aromatic system can contribute to bioactivity.
• Ligand Synthesis: Serves as a starting material for creating chiral ligands used in asymmetric catalysis to induce stereoselectivity in chemical reactions.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Material Science Research: Potential monomer or functionalization agent for advanced polymers and specialty materials requiring specific optical or electronic properties.

Basic Information

Product Name	(R)-(5-Bromo-2-Fluorophenyl)(Cyclopropyl)Methanamine
CAS No.	1213896-54-8
Molecular Formula	C10H11BrFN
Molecular Weight	244.10 g/mol
Synonyms	(R)-1-(5-Bromo-2-fluorophenyl)-1-cyclopropylmethanamine; (R)-α-Cyclopropyl-5-bromo-2-fluorobenzylamine; (R)-(5-Bromo-2-fluorobenzyl)(cyclopropyl)amine; (R)-[1-(5-Bromo-2-fluorophenyl)cyclopropyl]methanamine; (R)-Bromofluorophenylcyclopropylmethanamine; (R)-Enantiomer of 1213896-54-8
EINECS	Contact for details

Quality Control

Our production of (R)-(5-Bromo-2-Fluorophenyl)(Cyclopropyl)Methanamine adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by advanced analytical techniques including chiral HPLC, NMR, and MS. Certificates of Analysis (COA) detailing purity, chiral excess, and impurity profiles are provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.