Description

(S)-2,2,2-Trifluoro-1-(3-Isopropoxy-Phenyl)-Ethylamine is a high-purity chiral amine building block of significant importance in modern pharmaceutical and agrochemical research. Its core value lies in its trifluoromethyl group and chiral center, which are critical for modulating the biological activity, metabolic stability, and lipophilicity of target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical industry for the synthesis of novel active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of central nervous system (CNS) drugs, enzyme inhibitors, and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the trifluoromethyl group enhances efficacy.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorinated Compound Library: An essential building block for creating diverse fluorinated compound libraries for high-throughput screening in drug discovery.
• Process Chemistry: Employed in route scouting and scale-up studies for the commercial manufacturing of complex organic molecules.
• Academic Research: Utilized in universities and research institutes for studies in medicinal chemistry, organic synthesis, and fluorine chemistry.

Basic Information

Product Name	(S)-2,2,2-Trifluoro-1-(3-Isopropoxy-Phenyl)-Ethylamine
CAS No.	1213570-95-6
Molecular Formula	C11H14F3NO
Molecular Weight	233.23 g/mol
Synonyms	(S)-1-(3-Isopropoxyphenyl)-2,2,2-trifluoroethanamine; (S)-α-(Trifluoromethyl)-3-isopropoxybenzeneethanamine; (S)-2,2,2-Trifluoro-1-(3-isopropoxyphenyl)ethan-1-amine; (S)-1-(3-(Isopropoxy)phenyl)-2,2,2-trifluoroethylamine; (S)-3-Isopropoxy-α-(trifluoromethyl)benzeneethanamine; (S)-TFIPA; (S)-Trifluoroethylamine isopropoxy phenyl derivative
EINECS	Contact for details

Quality Control

Our (S)-2,2,2-Trifluoro-1-(3-Isopropoxy-Phenyl)-Ethylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with research and development standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.