Description

3-((1R)-1-Aminoethyl)-5-(Trifluoromethyl)Phenylamine is a high-purity chiral amine building block of significant interest in advanced organic synthesis. Its value lies in the combination of a stereogenic center and a trifluoromethyl group, which are critical motifs for modulating the biological activity and physicochemical properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine chemicals.

Application

• Key chiral intermediate in the synthesis of pharmaceutical candidates, especially for central nervous system (CNS) and metabolic disease targets.
• Building block for advanced agrochemicals, leveraging the trifluoromethyl group to enhance lipophilicity and metabolic stability.
• Precursor for chiral ligands and catalysts used in asymmetric synthesis.
• Intermediate in the development of specialty materials, such as liquid crystals or advanced polymers with tailored properties.
• Reference standard for analytical method development and quality control in chemical production.
• Starting material for the synthesis of complex molecules in academic and industrial research settings.

Basic Information

Product Name	3-((1R)-1-Aminoethyl)-5-(Trifluoromethyl)Phenylamine
CAS No.	1213552-98-7
Molecular Formula	C9H11F3N2
Molecular Weight	204.19 g/mol
Synonyms	(1R)-1-[3-Amino-5-(trifluoromethyl)phenyl]ethanamine; (R)-1-(3-Amino-5-(trifluoromethyl)phenyl)ethanamine; 5-(Trifluoromethyl)-3-[(1R)-1-aminoethyl]aniline; 3-[(1R)-1-Aminoethyl]-5-(trifluoromethyl)aniline; 3-[(R)-1-Aminoethyl]-5-(trifluoromethyl)aniline; (R)-3-Amino-α-methyl-5-(trifluoromethyl)benzenemethanamine; Benzenemethanamine, 3-amino-α-methyl-5-(trifluoromethyl)-, (αR)-
EINECS	Contact for details

Quality Control

Our 3-((1R)-1-Aminoethyl)-5-(Trifluoromethyl)Phenylamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including chiral purity (enantiomeric excess) and chemical purity, verified by techniques such as HPLC, GC, and NMR. Certificates of Analysis (COA) are available for every batch upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.