Description

(1R)-2,2,2-Trifluoro-1-(3,4,5-Trifluorophenyl)Ethylamine is a high-value, chiral fluorinated amine building block of significant interest in advanced organic synthesis. Its core value proposition lies in its unique stereochemistry and the presence of multiple fluorine atoms, which are critical for modulating the physicochemical and metabolic properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in CNS and metabolic disease areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where fluorine substitution enhances bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers and liquid crystals with specialized properties.
• Positron Emission Tomography (PET) Tracer Precursor: Potential use as a building block for fluorine-18 labeled radiopharmaceuticals for medical imaging.

Basic Information

Product Name	(1R)-2,2,2-Trifluoro-1-(3,4,5-Trifluorophenyl)Ethylamine
CAS No.	1213031-93-6
Molecular Formula	C8H5F6N
Molecular Weight	229.12 g/mol
Synonyms	(1R)-1-(3,4,5-Trifluorophenyl)-2,2,2-trifluoroethanamine; (R)-1-(3,4,5-Trifluorophenyl)-2,2,2-trifluoroethylamine; (R)-α-(Trifluoromethyl)-3,4,5-trifluorobenzeneethanamine; (R)-3,4,5-Trifluoro-α-(trifluoromethyl)benzylamine; (1R)-2,2,2-Trifluoro-1-(3,4,5-trifluorophenyl)ethanamine; (R)-TFMPEA; (R)-1-(Perfluorophenyl)-2,2,2-trifluoroethylamine (common name variant)
EINECS	Contact for details

Quality Control

Our (1R)-2,2,2-Trifluoro-1-(3,4,5-Trifluorophenyl)Ethylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and GC/HPLC for chemical purity, to ensure compliance with exacting R&D and process chemistry standards. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.