Description

(1R)-1-(3-Bromo-4-Fluorophenyl)Ethanamine CAS NO 1212423-60-3 is a chiral amine building block of significant interest in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecules with specific stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of new chiral compounds.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly in central nervous system (CNS) and oncology drug candidates.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure pesticides and herbicides where specific stereochemistry enhances efficacy and reduces environmental impact.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with tailored optical or electronic properties.
• Chemical Biology Probes: Useful for creating labeled compounds and molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	(1R)-1-(3-Bromo-4-Fluorophenyl)Ethanamine
CAS No.	1212423-60-3
Molecular Formula	C8H9BrFN
Molecular Weight	218.07 g/mol
Synonyms	(R)-1-(3-Bromo-4-fluorophenyl)ethanamine; (1R)-1-(3-Bromo-4-fluorophenyl)ethylamine; (R)-1-(3-Bromo-4-fluorophenyl)ethylamine; (R)-α-Methyl-3-bromo-4-fluoro-benzeneethanamine; (R)-3'-Bromo-4'-fluoro-α-methylbenzylamine; (R)-1-(3-Bromo-4-fluorophenyl)ethan-1-amine
EINECS	Contact for details

Quality Control

Our (1R)-1-(3-Bromo-4-Fluorophenyl)Ethanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure high chemical and optical purity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee consistent quality and traceability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.