Description

α-Me-Phe(2-Br)-Oh·H 2 O is a specialized, non-natural amino acid derivative featuring a brominated aromatic ring and a methylated α-carbon. This compound matters as a high-value, versatile chiral building block for the synthesis of complex bioactive molecules, offering unique steric and electronic properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, peptide mimetics, and advanced material science.

Application

• Key chiral intermediate in the synthesis of novel pharmaceutical candidates and active pharmaceutical ingredients (APIs).
• Building block for constructing constrained peptides and peptidomimetics with enhanced metabolic stability.
• Precursor for advanced ligands and catalysts used in asymmetric synthesis.
• Research reagent in medicinal chemistry for structure-activity relationship (SAR) studies.
• Starting material for the development of specialized agrochemicals and fine chemicals.
• Component in the synthesis of custom amino acids for biochemical research and diagnostic applications.

Basic Information

Product Name	α-Me-Phe(2-Br)-Oh·H 2 O
CAS No.	1212180-27-2
Molecular Formula	C₁₀H₁₂BrNO₃
Molecular Weight	274.11 g/mol (Anhydrous Basis)
Synonyms	(2S)-2-Amino-3-(2-bromophenyl)-2-methylpropanoic acid hydrate; 2-Bromo-α-methyl-L-phenylalanine hydrate; (S)-2-Amino-3-(2-bromophenyl)-2-methylpropanoic acid monohydrate; L-α-Methyl-2-bromophenylalanine hydrate; (S)-α-Methyl-2-bromophenylalanine; Boc-α-Me-Phe(2-Br)-OH precursor; Fmoc-α-Me-Phe(2-Br)-OH precursor; Non-natural brominated phenylalanine derivative
EINECS	Contact for details

Quality Control

Our α-Me-Phe(2-Br)-Oh·H 2 O is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee reproducible results and supply chain reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	5.0 - 8.0% (Theoretical for monohydrate: ~6.6%)
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.