Description

n-(3-(Dimethylamino)Propyl)-4-(4-Fluoro-2-Isopropoxyphenylamino)-5-Methylthieno[2,3-D]Pyrimidine-6-Carboxamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of targeted kinase inhibitors. It is primarily sought after by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel kinase inhibitor drug candidates for oncology and inflammatory diseases.
• Biochemical Research: Used as a reference standard or active compound in high-throughput screening (HTS) and structure-activity relationship (SAR) studies.
• Preclinical Development: Serves as a critical material for pharmacokinetic, pharmacodynamic, and toxicology studies during drug discovery phases.
• Academic Research: Employed in university and institutional labs for investigating signal transduction pathways and enzyme inhibition mechanisms.
• Custom Synthesis: Starting point for the custom synthesis of more complex, proprietary molecules for client-specific drug development programs.

Basic Information

Item	Detail
Product Name	n-(3-(Dimethylamino)Propyl)-4-(4-Fluoro-2-Isopropoxyphenylamino)-5-Methylthieno[2,3-D]Pyrimidine-6-Carboxamide
CAS No.	1211758-28-9
Molecular Formula	C22H28FN5O2S
Molecular Weight	445.55 g/mol
Synonyms	4-((4-Fluoro-2-isopropoxyphenyl)amino)-5-methyl-N-(3-(dimethylamino)propyl)thieno[2,3-d]pyrimidine-6-carboxamide; 1211758-28-9; Thieno[2,3-d]pyrimidine-6-carboxamide derivative; Kinase inhibitor intermediate; CAS 1211758-28-9
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and LC-MS to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development under cGMP guidelines where required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.