Description

2-Chloro-5-Fluoropyrimidine-4-Carboxylic Acid is a high-value halogenated pyrimidine derivative, serving as a critical building block in modern synthetic chemistry. Its molecular architecture makes it an essential intermediate for the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of antiviral, anticancer, and other biologically active molecules.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization (e.g., amidation, esterification) to create diverse pyrimidine libraries.
• Material Science: Potential building block for organic electronic materials and ligands in catalytic systems.
• Contract Research & Development (CRO/CMO): Supplied to organizations for custom synthesis and process development projects.

Basic Information

Product Name	2-Chloro-5-Fluoropyrimidine-4-Carboxylic Acid
CAS No.	1211588-45-2
Molecular Formula	C5H2ClFN2O2
Molecular Weight	176.53 g/mol
Synonyms	2-Chloro-5-fluoropyrimidine-4-carboxylic acid; 4-Pyrimidinecarboxylic acid, 2-chloro-5-fluoro-; 5-Fluoro-2-chloropyrimidine-4-carboxylic acid; 2-Chloro-5-fluoro-4-pyrimidinecarboxylic acid; 1211588-45-2; 2-Chloro-5-fluoropyrimidine-4-carboxylate
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-Fluoropyrimidine-4-Carboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and synthesis. A detailed Certificate of Analysis (COA) including HPLC purity, identity confirmation (NMR, IR), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.