Description

4-Chloro-5-Fluoro-7H-Pyrrolo[2,3-D]Pyrimidine is a high-value, multi-functional heterocyclic building block essential for modern synthetic chemistry. Its core value lies in its unique halogenated pyrrolopyrimidine scaffold, which serves as a privileged structure for designing novel bioactive molecules. This compound is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs), particularly in oncology and antiviral therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors and other targeted cancer therapies.
• Agrochemical Research: Used as a key scaffold for developing new herbicides and fungicides with novel modes of action.
• Biochemical Probe Development: Serves as a core structure for creating tool compounds to study enzyme function and cellular signaling pathways.
• Material Science: Potential building block for advanced organic electronic materials due to its fused heteroaromatic system.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and medicinal chemistry services.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and fluorine chemistry.

Basic Information

Product Name	4-Chloro-5-Fluoro-7H-Pyrrolo[2,3-D]Pyrimidine
CAS No.	1211587-23-3
Molecular Formula	C6H3ClFN3
Molecular Weight	171.56 g/mol
Synonyms	4-Chloro-5-fluoropyrrolo[2,3-d]pyrimidine; 4-Chloro-5-fluoro-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-5-fluoro-; 4-Chloro-5-fluoro-7H-pyrrolo[2,3-d]pyrimidine; 4-Chloro-5-fluoro-7-azaindole; 4-Chloro-5-fluoro-7-deazapurine
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Fluoro-7H-Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and KF for moisture content, to ensure it meets the stringent requirements of pharmaceutical development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.