Description

2-Cyclopropylpyrimidine-4-Carboxylic Acid is a high-purity pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its unique cyclopropyl-substituted pyrimidine core makes it a valuable scaffold for developing novel pharmacologically active compounds. This intermediate is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and investigational new drugs, particularly those targeting kinase inhibition.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Serves as a building block for creating novel herbicides and fungicides with specific modes of action.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Material Science: Potential intermediate for the development of specialty polymers and organic electronic materials.

Basic Information

Product Name	2-Cyclopropylpyrimidine-4-Carboxylic Acid
CAS No.	1211533-70-8
Molecular Formula	C8H8N2O2
Molecular Weight	164.16 g/mol
Synonyms	4-Pyrimidinecarboxylic acid, 2-cyclopropyl-; 2-Cyclopropyl-4-pyrimidinecarboxylic acid; Cyclopropanepyrimidine-4-carboxylic acid; 2-Cyclopropylpyrimidine-4-carboxylic acid; 1211533-70-8; 2-Cyclopropyl-1,3-diazine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Cyclopropylpyrimidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications. We support cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.