Description

5-Fluoropyrimidine-4-Carboxylic Acid is a high-purity fluorinated heterocyclic building block essential for advanced organic synthesis. This compound is valued for its role as a key precursor in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical synthon for the research and development of fluorinated drug candidates, particularly in oncology and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and stability.
• Chemical Research: Serves as a versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential application in the synthesis of specialty polymers and ligands for catalytic systems.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP guidelines.

Basic Information

Product Name	5-Fluoropyrimidine-4-Carboxylic Acid
CAS No.	1211528-24-3
Molecular Formula	C5H3FN2O2
Molecular Weight	142.09 g/mol
Synonyms	4-Pyrimidinecarboxylic acid, 5-fluoro-; 5-Fluoro-4-pyrimidinecarboxylic acid; 5-Fluoropyrimidine-4-carboxylic acid; 5-Fluoro-1,3-diazine-4-carboxylic acid; 5-Fluoropyrimidine-4-carboxylate; 5-Fluoro-4-carboxypyrimidine; 1211528-24-3
EINECS	Contact for details

Quality Control

Our 5-Fluoropyrimidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.