Description

4-Chloro-5H-Pyrimido[4,5-B][1,4]Oxazin-6(7H)-One is a high-value heterocyclic organic compound featuring a fused pyrimidine-oxazine core structure. This specialized chemical building block is critical for advanced research and development in medicinal chemistry, enabling the synthesis of novel pharmacologically active molecules. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly for oncology and targeted disease pathways.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel small-molecule drug candidates, particularly kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Biology Probe Development: Employed in the design and synthesis of chemical probes to study specific biological pathways and protein functions.
• Agrochemical Research: Potential application as an intermediate in the synthesis of new active ingredients for crop protection products.
• Academic & Institutional R&D: Utilized in universities and research institutes for fundamental studies in heterocyclic chemistry and organic synthesis methodologies.

Basic Information

Product Name	4-Chloro-5H-Pyrimido[4,5-B][1,4]Oxazin-6(7H)-One
CAS No.	1211524-67-2
Molecular Formula	C6H4ClN3O2
Molecular Weight	185.57 g/mol
Synonyms	4-Chloro-5H-pyrimido[4,5-b][1,4]oxazin-6(7H)-one; 4-Chloro-7H-pyrimido[4,5-b][1,4]oxazin-6-one; 4-Chloro-5,7-dihydropyrimido[4,5-b][1,4]oxazin-6-one; 1211524-67-2; 4-Chloro-5H-pyrimido[4,5-b]-1,4-oxazin-6(7H)-one; 4-Chloro-7H-pyrimido[4,5-b][1,4]oxazine-6-one; 4-Chloro-5H-[1,4]oxazino[4,5-b]pyrimidin-6(7H)-one
EINECS	Contact for details

Quality Control

Our 4-Chloro-5H-Pyrimido[4,5-B][1,4]Oxazin-6(7H)-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.