Description

2-Chloro-7-Cyclopentyl-7H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxylic Acid is a high-value, advanced pharmaceutical intermediate belonging to the pyrrolopyrimidine class of heterocyclic compounds. This compound is critical for research and development in medicinal chemistry, particularly for its role as a key building block in the synthesis of targeted kinase inhibitors. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the development of novel therapeutic agents for oncology and inflammatory diseases.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of potent and selective kinase inhibitors targeting various disease pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Bioconjugation & Probe Development: The carboxylic acid functional group allows for conjugation to carriers, labels, or other molecules to create biochemical probes.
• Process Chemistry & Scale-Up: Used in the development and optimization of robust, scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for fundamental studies in organic synthesis and chemical biology.

Basic Information

Item	Detail
Product Name	2-Chloro-7-Cyclopentyl-7H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxylic Acid
CAS No.	1211443-58-1
Molecular Formula	C12H12ClN3O2
Molecular Weight	265.70 g/mol
Synonyms	2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid; 7-Cyclopentyl-2-chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic Acid; 1211443-58-1; 2-Chloro-7-cyclopentyl-6-carboxy-7H-pyrrolo[2,3-d]pyrimidine; Pyrrolo[2,3-d]pyrimidine-6-carboxylic acid, 2-chloro-7-cyclopentyl-7H-
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-7-Cyclopentyl-7H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxylic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP standards for advanced intermediates used in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The material should be kept under an inert atmosphere for long-term storage to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.