Description

4-Bromo-5-Methoxypyrimidine is a versatile halogenated pyrimidine derivative, a crucial building block in modern synthetic organic chemistry. Its core value lies in enabling the precise construction of complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate and scale novel compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of nucleoside analogs, kinase inhibitors, and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging the pyrimidine core's bioactivity.
• Material Science: Serves as a precursor for functionalized ligands in catalysis and as a monomer or cross-linker in the synthesis of specialty polymers.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitution reactions to introduce the 4-bromo-5-methoxypyrimidine moiety into more complex structures.
• Life Sciences & Diagnostics: Utilized in the preparation of labeled compounds, probes, and other tools for biochemical research and diagnostic applications.

Basic Information

Product Name	4-Bromo-5-Methoxypyrimidine
CAS No.	1211184-80-3
Molecular Formula	C5H5BrN2O
Molecular Weight	189.01 g/mol
Synonyms	5-Methoxy-4-bromopyrimidine; 4-Bromo-5-methoxy-pyrimidine; Pyrimidine, 4-bromo-5-methoxy-; 4-Brom-5-methoxypyrimidin (German); 4-ブロモ-5-メトキシピリミジン (Japanese)
EINECS	Contact for details

Quality Control

Our 4-Bromo-5-Methoxypyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is available for every batch upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.