Description

2-Amino-1-(3,4-Difluorophenyl)-Ethanone Hcl is a high-purity organic intermediate featuring a difluorophenyl ketone scaffold with a primary amine hydrochloride salt. This compound is critical for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the difluorophenyl moiety.
• Chemical Synthesis: Serves as a versatile precursor for the preparation of more complex heterocyclic compounds, such as imidazoles and oxazoles.
• Material Science: Potential intermediate in the synthesis of specialty polymers and advanced organic electronic materials.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for medicinal chemistry programs and methodological studies.

Basic Information

Product Name	2-Amino-1-(3,4-Difluorophenyl)-Ethanone Hydrochloride
CAS No.	1209894-23-4
Molecular Formula	C8H8F2NO•HCl
Molecular Weight	207.61 (Free base) / 244.07 (HCl salt)
Synonyms	1-(3,4-Difluorophenyl)-2-aminoethanone hydrochloride; 2-Amino-1-(3,4-difluorophenyl)ethan-1-one hydrochloride; 3',4'-Difluoro-2-aminoacetophenone hydrochloride; α-Amino-3,4-difluoroacetophenone hydrochloride; 2-Amino-3',4'-difluoroacetophenone HCl; Amino difluorophenyl ketone hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Amino-1-(3,4-Difluorophenyl)-Ethanone Hcl is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.