Description

Ethyl 4-Chloro-1H-Pyrrolo[2,3-D]Pyrimidine-2-Carboxylate is a high-purity heterocyclic building block of significant importance in modern organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical agents, particularly kinase inhibitors and other targeted therapeutics. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various diseases.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies due to its versatile pyrrolopyrimidine scaffold.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes for Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the life sciences industry.

Basic Information

Product Name	Ethyl 4-Chloro-1H-Pyrrolo[2,3-D]Pyrimidine-2-Carboxylate
CAS No.	1209749-81-4
Molecular Formula	C9H8ClN3O2
Molecular Weight	225.63 g/mol
Synonyms	4-Chloro-1H-pyrrolo[2,3-d]pyrimidine-2-carboxylic acid ethyl ester; Ethyl 4-chloro-1H-pyrrolo[2,3-d]pyrimidine-2-carboxylate; 1H-Pyrrolo[2,3-d]pyrimidine-2-carboxylic acid, 4-chloro-, ethyl ester; 4-Chloro-1H-pyrrolo[2,3-d]pyrimidine-2-carboxylate ethyl ester; 4-Chloro-1H-pyrrolo[2,3-d]pyrimidine-2-carboxylic acid ethyl ester; Ethyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-2-carboxylate; 1209749-81-4
EINECS	Contact for details

Quality Control

Our Ethyl 4-Chloro-1H-Pyrrolo[2,3-D]Pyrimidine-2-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive analytical data, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) are available for every batch upon request, detailing purity and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.