Description

4,6-Dichloro-5-(5-(Trifluoromethyl)benzo[d]thiazol-2-yl)pyrimidin-2-amine is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure. This compound is of significant commercial importance for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in developing new drug candidates and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its heterocyclic core for bioactivity.
• Chemical Biology: Employed as a molecular probe or scaffold in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Material Science: Potential use in the synthesis of organic electronic materials due to its electron-deficient aromatic system.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	4,6-Dichloro-5-(5-(trifluoromethyl)benzo[d]thiazol-2-yl)pyrimidin-2-amine
CAS No.	1208987-38-5
Molecular Formula	C12H5Cl2F3N4S
Molecular Weight	365.16 g/mol
Synonyms	4,6-Dichloro-5-[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]pyrimidin-2-amine; 2-Amino-4,6-dichloro-5-(5-trifluoromethylbenzothiazol-2-yl)pyrimidine; 1208987-38-5; 4,6-Dichloro-5-(5-(trifluoromethyl)-1,3-benzothiazol-2-yl)-2-pyrimidinamine; 5-(5-(Trifluoromethyl)benzo[d]thiazol-2-yl)-4,6-dichloropyrimidin-2-amine
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-5-(5-(trifluoromethyl)benzo[d]thiazol-2-yl)pyrimidin-2-amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.