Description

2,4-Dichloro-5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of targeted therapeutic agents, offering researchers and manufacturers a reliable building block for complex molecular architectures. It is primarily utilized by pharmaceutical R&D teams and fine chemical producers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly in oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of novel drug candidates, especially kinase inhibitors.
• Oncology Research: Used in the synthesis of potential therapeutic agents targeting specific cancer pathways.
• Medicinal Chemistry: Provides a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex nitrogen-containing heterocycles.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of clinical trial materials and commercial APIs.
• Biochemical Research: Used as a tool compound in biochemical assays to study enzyme function and cellular signaling.

Basic Information

Product Name	2,4-Dichloro-5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidine Hydrochloride
CAS No.	1208901-69-2
Molecular Formula	C7H8Cl3N3
Molecular Weight	264.52 g/mol
Synonyms	2,4-Dichloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine HCl; 2,4-Dichloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine hydrochloride; 5,6,7,8-Tetrahydro-2,4-dichloropyrido[4,3-d]pyrimidine hydrochloride; 2,4-Dichloro-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine hydrochloride; Pyrido[4,3-d]pyrimidine, 2,4-dichloro-5,6,7,8-tetrahydro-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.