Description

2-Chloro-4-Fluoro-5-Methylbenzenesulfonyl Chloride is a high-purity, multi-functional sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual reactive sites, enabling the efficient introduction of the sulfonyl moiety and facilitating further functionalization for complex molecule construction. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and pesticides that require specific halogenated sulfonyl structures for enhanced activity.
• Material Science: Used in the development of specialty polymers, dyes, and liquid crystals where sulfonyl groups modify physical properties.
• Chemical Research: A versatile reagent for academic and industrial R&D in exploring new reaction pathways and creating compound libraries.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Item	Details
Product Name	2-Chloro-4-Fluoro-5-Methylbenzenesulfonyl Chloride
CAS No.	1208076-71-4
Molecular Formula	C7H5Cl2FO2S
Molecular Weight	247.08 g/mol
Synonyms	2-Chloro-4-fluoro-5-methylbenzene-1-sulfonyl chloride; 5-Methyl-2-chloro-4-fluorobenzenesulfonyl chloride; 1-Chlorosulfonyl-2-chloro-4-fluoro-5-methylbenzene; Benzenesulfonyl chloride, 2-chloro-4-fluoro-5-methyl-; 2-Chloro-4-fluoro-5-methyl-1-sulfonyl chloride benzene
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluoro-5-Methylbenzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.