Description

Ethyl 2-Bromopyrimidine-4-Carboxylate is a high-purity brominated pyrimidine derivative, serving as a critical building block in modern synthetic organic chemistry. Its value lies in its versatile reactivity, where the bromine atom and ester group provide distinct handles for selective functionalization, enabling the efficient construction of complex heterocyclic scaffolds. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used to construct novel pyrimidine-based herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Serves as a monomer or functionalizing agent in the development of advanced organic electronic materials and liquid crystals.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitution reactions to introduce the pyrimidine core into more complex molecular architectures.
• Academic & R&D: A valuable reagent for methodological development and exploring new reaction pathways in heterocyclic and medicinal chemistry.

Basic Information

Product Name	Ethyl 2-Bromopyrimidine-4-Carboxylate
CAS No.	1207954-85-5
Molecular Formula	C7H7BrN2O2
Molecular Weight	231.05 g/mol
Synonyms	2-Bromopyrimidine-4-carboxylic acid ethyl ester; Ethyl 2-bromo-4-pyrimidinecarboxylate; 4-Pyrimidinecarboxylic acid, 2-bromo-, ethyl ester; 2-Bromo-4-(ethoxycarbonyl)pyrimidine; Ethyl 2-bromopyrimidine-4-carboxylate; 1207954-85-5
EINECS	Contact for details

Quality Control

Our Ethyl 2-Bromopyrimidine-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if possible. Keep away from heat and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.