Description

4-Chloro-1-(3-Methylpyridin-4-Yl)-1H-Pyrazolo[3,4-D]Pyrimidine is a high-value, heterocyclic organic compound that serves as a critical synthetic intermediate in modern pharmaceutical research and development. Its core value lies in its versatile pyrazolopyrimidine scaffold, which is a privileged structure for designing potent kinase inhibitors and other biologically active molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of targeted cancer therapies, particularly kinase inhibitors.
• Biochemical Research: Used as a reference standard or a precursor in the study of enzyme inhibition and cellular signaling pathways.
• Medicinal Chemistry: Core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs developing proprietary compounds for clients.
• Academic Research: Utilized in universities and research institutes for exploring new chemical entities and their biological activities.

Basic Information

Product Name	4-Chloro-1-(3-Methylpyridin-4-Yl)-1H-Pyrazolo[3,4-D]Pyrimidine
CAS No.	1207827-22-2
Molecular Formula	C11H8ClN5
Molecular Weight	245.67 g/mol
Synonyms	4-Chloro-1-(3-methyl-4-pyridinyl)-1H-pyrazolo[3,4-d]pyrimidine; 1H-Pyrazolo[3,4-d]pyrimidine, 4-chloro-1-(3-methyl-4-pyridinyl)-; 4-Chloro-1-(3-methylpyridin-4-yl)-1H-pyrazolo[3,4-d]pyrimidine; UNII-9J6I9V16YI; 9J6I9V16YI; BDBM50388885; AKOS025147064; ZINC000253914977
EINECS	Contact for details

Quality Control

Our 4-Chloro-1-(3-Methylpyridin-4-Yl)-1H-Pyrazolo[3,4-D]Pyrimidine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. All batches are characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.