Description

Pyrido[3,4-D]Pyrimidine-7(6H)-Carboxylic Acid, 2-[4-[[(Ethylamino)Carbonyl]Amino]Phenyl]-5,8-Dihydro-4-[(3S)-3-Methyl-4-Morpholinyl]-, 1,1-Dimethylethyl Ester is a high-purity, complex heterocyclic building block designed for advanced pharmaceutical research and development. This compound is a critical intermediate in the synthesis of targeted therapeutic agents, offering precise structural control for medicinal chemists. It is primarily utilized by R&D teams in the pharmaceutical and biotechnology sectors for the development of novel small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel kinase inhibitors and other targeted small-molecule therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its complex, functionalized pyridopyrimidine core.
• Preclinical Drug Development: Serves as a critical intermediate for producing candidate compounds for pharmacological and toxicological evaluation.
• Chemical Biology Probes: Employed in the development of chemical probes to study specific biological pathways and protein functions.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Item	Details
Product Name	Pyrido[3,4-D]Pyrimidine-7(6H)-Carboxylic Acid, 2-[4-[[(Ethylamino)Carbonyl]Amino]Phenyl]-5,8-Dihydro-4-[(3S)-3-Methyl-4-Morpholinyl]-, 1,1-Dimethylethyl Ester
CAS No.	1207365-47-6
Molecular Formula	C26H36N6O5
Molecular Weight	512.60 g/mol
Synonyms	tert-Butyl 2-(4-(3-ethylureido)phenyl)-4-((S)-3-methylmorpholino)-5,8-dihydropyrido[3,4-d]pyrimidine-7(6H)-carboxylate; 1,1-Dimethylethyl 2-[4-[[(ethylamino)carbonyl]amino]phenyl]-5,8-dihydro-4-[(3S)-3-methyl-4-morpholinyl]pyrido[3,4-d]pyrimidine-7(6H)-carboxylate; UNII-1V8P8N2799; 1V8P8N2799; BDBM50388825; AKOS025147065; ZINC000006889956; (3S)-tert-Butyl 2-(4-(3-ethylureido)phenyl)-4-(3-methylmorpholino)-5,8-dihydropyrido[3,4-d]pyrimidine-7(6H)-carboxylate
EINECS	Contact for details

Quality Control

Our Pyrido[3,4-D]Pyrimidine-7(6H)-Carboxylic Acid, 2-[4-[[(Ethylamino)Carbonyl]Amino]Phenyl]-5,8-Dihydro-4-[(3S)-3-Methyl-4-Morpholinyl]-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed under inert atmosphere if necessary and opened only in a dry environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.