Description

tert-Butyl 5H-Pyrrolo[3,4-D]Pyrimidine-6(7H)-Carboxylate CAS NO 1207175-93-6 is a high-value, protected heterocyclic building block essential for modern pharmaceutical research and development. This compound serves as a critical intermediate in the synthesis of complex molecules, enabling the exploration of novel therapeutic agents. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for constructing kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for kinase-targeted therapies.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to develop novel drug candidates.
• Process Chemistry & Scale-up: Serves as a building block for developing robust and scalable synthetic routes from laboratory to pilot plant scale.
• Bioconjugation & Probe Development: The reactive sites on the pyrrolopyrimidine core can be utilized for creating biochemical probes and diagnostic agents.
• Library Synthesis: Employed in combinatorial and parallel synthesis to generate diverse compound libraries for high-throughput screening.

Basic Information

Product Name	tert-Butyl 5H-Pyrrolo[3,4-D]Pyrimidine-6(7H)-Carboxylate
CAS No.	1207175-93-6
Molecular Formula	C11H15N3O2
Molecular Weight	221.26 g/mol
Synonyms	6-(tert-Butoxycarbonyl)-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidine; tert-Butyl 5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxylate; 6-Boc-5,6,7,8-tetrahydropyrrolo[3,4-d]pyrimidine; Boc-protected pyrrolopyrimidine; 1207175-93-6; Pyrrolo[3,4-d]pyrimidine-6(7H)-carboxylic acid, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 5H-Pyrrolo[3,4-D]Pyrimidine-6(7H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible to maximize shelf life.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.