Description

4-(Prop-1-Ynyl)Pyrimidin-2-Amine CAS NO 1207175-48-1 is a specialized pyrimidine derivative featuring a terminal alkyne functional group, making it a valuable building block in advanced organic synthesis. This compound is critical for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where precise molecular architecture is required. It is primarily targeted at the pharmaceutical, agrochemical, and advanced materials research sectors for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the synthesis of new generation herbicides, fungicides, and plant growth regulators.
• Chemical Biology & Proteomics: The alkyne moiety enables click chemistry applications, such as bioconjugation and activity-based protein profiling (ABPP).
• Material Science: Acts as a monomer or precursor for constructing functional polymers and organic electronic materials.
• Academic & Contract Research: Essential for exploratory research in heterocyclic and medicinal chemistry within universities and CROs.
• Custom Synthesis: A starting point for the contract manufacturing of complex, proprietary molecules for client-specific projects.

Basic Information

Product Name	4-(Prop-1-Ynyl)Pyrimidin-2-Amine
CAS No.	1207175-48-1
Molecular Formula	C7H7N3
Molecular Weight	133.15 g/mol
Synonyms	4-(Prop-1-yn-1-yl)pyrimidin-2-amine; 2-Amino-4-(prop-1-yn-1-yl)pyrimidine; 4-Prop-1-ynylpyrimidin-2-ylamine; 4-(1-Propynyl)-2-pyrimidinamine; 4-Propynyl-2-aminopyrimidine; 2-Pyrimidinamine, 4-(1-propyn-1-yl)-; 1207175-48-1
EINECS	Contact for details

Quality Control

Our 4-(Prop-1-Ynyl)Pyrimidin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). As a fine chemical, it should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.