Description

2-(5-Amino-3-Cyclopropyl-1H-Pyrazol-1-Yl)-5-Ethyl-6-Methylpyrimidin-4(3H)-One is a high-value, heterocyclic organic compound featuring a fused pyrazole-pyrimidinone structure, serving as a critical advanced intermediate in modern synthetic chemistry. Its molecular architecture makes it a versatile building block for constructing complex pharmacophores, directly addressing the need for novel chemical entities in drug discovery. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly for targeting specific enzymatic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis to explore new biological targets.
• Agrochemical Development: Serves as a building block for creating new candidates in crop protection and pesticide research.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and cellular processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized compounds under cGMP conditions.

Basic Information

Product Name	2-(5-Amino-3-Cyclopropyl-1H-Pyrazol-1-Yl)-5-Ethyl-6-Methylpyrimidin-4(3H)-One
CAS No.	1207047-57-1
Molecular Formula	C13H17N5O
Molecular Weight	259.31 g/mol
Synonyms	5-Ethyl-6-methyl-2-(5-amino-3-cyclopropyl-1H-pyrazol-1-yl)pyrimidin-4(3H)-one; 2-(5-Amino-3-cyclopropyl-1H-pyrazol-1-yl)-5-ethyl-6-methyl-3,4-dihydropyrimidin-4-one; 1207047-57-1; 5-Ethyl-6-methyl-2-(5-amino-3-cyclopropylpyrazol-1-yl)pyrimidin-4-ol; Pyrimidin-4(3H)-one, 2-(5-amino-3-cyclopropyl-1H-pyrazol-1-yl)-5-ethyl-6-methyl-
EINECS	Contact for details

Quality Control

Our production of 2-(5-Amino-3-Cyclopropyl-1H-Pyrazol-1-Yl)-5-Ethyl-6-Methylpyrimidin-4(3H)-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support development projects with material produced under quality systems suitable for non-GMP and cGMP applications, with specifications tailored to client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.