Description

8-Methoxy-5H-Chromeno[4,3-D]Pyrimidine-2-Thiol is a high-purity, advanced pharmaceutical intermediate with a complex fused-ring structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates targeting various diseases.
• Organic Synthesis Building Block: Used in research-scale and process chemistry for constructing complex chromene and pyrimidine-containing molecules.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to develop new pharmacophores.
• Chemical Reference Standard: Acts as a high-purity standard for analytical method development and quality control in API manufacturing.
• Biochemical Research: Investigated for potential biological activity in various assay systems.

Basic Information

Product Name	8-Methoxy-5H-Chromeno[4,3-D]Pyrimidine-2-Thiol
CAS No.	1206969-45-0
Molecular Formula	C₁₂H₁₀N₂O₂S
Molecular Weight	246.29 g/mol
Synonyms	8-Methoxy-5H-chromeno[4,3-d]pyrimidine-2-thiol; 8-Methoxy-2-mercapto-5H-chromeno[4,3-d]pyrimidine; 5H-Chromeno[4,3-d]pyrimidine-2-thiol, 8-methoxy-; 1206969-45-0
EINECS	Contact for details

Quality Control

Our 8-Methoxy-5H-Chromeno[4,3-D]Pyrimidine-2-Thiol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere if long-term storage is required.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.