Description

2-Chloro-5H-Chromeno[4,3-D]Pyrimidine is a high-value, multi-fused heterocyclic compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique chromeno-pyrimidine scaffold makes it a versatile building block for the development of novel pharmacologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of potential drug candidates targeting various therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates for oncology, CNS disorders, and anti-inflammatory applications.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Biology Probe Development: Serves as a starting material for creating molecular probes to study biological pathways and protein functions.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to construct fused polycyclic systems of interest in material science and agrochemical research.
• Academic & Industrial R&D: Essential for fundamental research in heterocyclic chemistry and the development of new synthetic methodologies.

Basic Information

Product Name	2-Chloro-5H-Chromeno[4,3-D]Pyrimidine
CAS No.	1206969-15-4
Molecular Formula	C11H7ClN2O
Molecular Weight	218.64 g/mol
Synonyms	2-Chloro-5H-chromeno[4,3-d]pyrimidine; 5H-Chromeno[4,3-d]pyrimidine, 2-chloro-; 2-Chloro-5H-[1]benzopyrano[4,3-d]pyrimidine; 2-Chloro-5H-benzo[h]chromeno[4,3-d]pyrimidine (alternate numbering); Chromeno[4,3-d]pyrimidine, 2-chloro-5H-; CAS 1206969-15-4
EINECS	Contact for details

Quality Control

Our 2-Chloro-5H-Chromeno[4,3-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity assessment and NMR/LC-MS for structural confirmation, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.