Description

4-Chloro-5-Fluoro-2-Hydroxy-Benzaldehyde is a halogenated hydroxybenzaldehyde derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for constructing complex heterocyclic and pharmaceutical intermediates. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing benzofuran or quinazoline scaffolds.
• Agrochemical Synthesis: Used in the development of new herbicides and fungicides, leveraging its halogenated aromatic structure.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and liquid crystals.
• Chemical Research: A versatile starting material for palladium-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination.
• Dye and Pigment Intermediate: Utilized in the synthesis of complex organic dyes and colorants due to its aldehyde and phenolic functional groups.

Basic Information

Product Name	4-Chloro-5-Fluoro-2-Hydroxy-Benzaldehyde
CAS No.	1205551-36-5
Molecular Formula	C7H4ClFO2
Molecular Weight	174.56 g/mol
Synonyms	2-Hydroxy-4-chloro-5-fluorobenzaldehyde; 4-Chloro-5-fluoro-2-hydroxybenzenecarboxaldehyde; 5-Fluoro-4-chloro-2-hydroxybenzaldehyde; 4-Chloro-5-fluorosalicylaldehyde; 2-Formyl-5-fluoro-4-chlorophenol; 5-Fluoro-4-chlorosalicylaldehyde; 4-Chloro-5-fluoro-2-hydroxy-benzaldehyde
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Fluoro-2-Hydroxy-Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is light-sensitive and should be stored away from direct light. Due to its potential for oxidation, it is recommended to handle under an inert atmosphere for long-term storage or after opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.