Description

6-(Difluoromethyl)-2-Mercaptopyrimidin-4-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its unique difluoromethyl and mercapto functional groups. This compound is of significant commercial importance for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing next-generation therapeutics and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in antiviral, anticancer, and anti-inflammatory research pipelines.
• Agrochemical Synthesis: Serves as a key building block for developing new-generation fungicides and herbicides with enhanced efficacy.
• Chemical Research & Development: Used in academic and industrial R&D for exploring new heterocyclic chemistry and creating compound libraries for screening.
• Material Science: Potential application in the synthesis of specialized ligands or functional materials due to its unique sulfur and fluorine-containing structure.

Basic Information

Product Name	6-(Difluoromethyl)-2-Mercaptopyrimidin-4-Ol
CAS No.	1204298-76-9
Molecular Formula	C5H4F2N2OS
Molecular Weight	178.16 g/mol
Synonyms	6-(Difluoromethyl)-4-hydroxy-2-mercaptopyrimidine; 4-Hydroxy-6-(difluoromethyl)-2-pyrimidinethiol; 2-Mercapto-6-(difluoromethyl)pyrimidin-4-ol; 6-(Difluoromethyl)-2-thioxo-1,2-dihydropyrimidin-4-one; 4(1H)-Pyrimidinone, 6-(difluoromethyl)-2-mercapto-
EINECS	Contact for details

Quality Control

Our 6-(Difluoromethyl)-2-Mercaptopyrimidin-4-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and easily oxidized; it is recommended to store under an inert atmosphere such as nitrogen for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.