Description

4-Chloro-6-(Difluoromethyl)-2-(Methylthio)Pyrimidine is a high-value pyrimidine derivative, a crucial building block in advanced organic synthesis. Its molecular structure, featuring chloro, difluoromethyl, and methylthio substituents, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrimidine core.
• Material Science Research: Serves as a precursor for creating specialized ligands, functional polymers, and liquid crystals.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific halogenated and fluorinated heterocycles.
• Academic & Industrial R&D: Utilized in chemical libraries for high-throughput screening and structure-activity relationship (SAR) studies.

Basic Information

Product Name	4-Chloro-6-(Difluoromethyl)-2-(Methylthio)Pyrimidine
CAS No.	1204298-68-9
Molecular Formula	C6H5ClF2N2S
Molecular Weight	210.63 g/mol
Synonyms	4-Chloro-6-(difluoromethyl)-2-(methylsulfanyl)pyrimidine; 2-(Methylthio)-4-chloro-6-(difluoromethyl)pyrimidine; 4-Chloro-6-(difluoromethyl)-2-methylthiopyrimidine; 1204298-68-9; 4-Chloro-6-difluoromethyl-2-methylsulfanyl-pyrimidine; 4-Chloro-6-(difluoromethyl)-2-(methylmercapto)pyrimidine; Pyrimidine, 4-chloro-6-(difluoromethyl)-2-(methylthio)-
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-(Difluoromethyl)-2-(Methylthio)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/GC-MS)	Conforms
Assay (HPLC)	≥ 97.0%
Purity (by GC)	≥ 96.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.