Description

1-(4-Fluorobenzyl)-6-Mercapto-1,5-Dihydro-4H-Pyrazolo[3,4-D]Pyrimidin-4-One is a high-purity, advanced pharmaceutical intermediate critical for modern drug discovery and development. This compound is valued for its role as a versatile building block in synthesizing novel therapeutic agents, particularly kinase inhibitors. It is primarily required by research institutions and pharmaceutical manufacturers engaged in developing treatments for oncology, inflammatory diseases, and other targeted therapies.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel kinase inhibitors and other small-molecule drug candidates.
• Oncology Research: Used in the R&D of targeted cancer therapies due to its pyrazolopyrimidine core structure.
• Biochemical Research: Serves as a reference standard and a tool compound for enzymatic assays and biological pathway studies.
• Custom Synthesis: Building block for contract research organizations (CROs) and CDMOs for client-specific molecule development.
• Preclinical Development: Utilized in the early-stage development and scale-up of potential drug molecules.

Basic Information

Product Name	1-(4-Fluorobenzyl)-6-Mercapto-1,5-Dihydro-4H-Pyrazolo[3,4-D]Pyrimidin-4-One
CAS No.	1204298-15-6
Molecular Formula	C₁₂H₉FN₄OS
Molecular Weight	276.29 g/mol
Synonyms	1-[(4-Fluorophenyl)methyl]-6-sulfanylidene-5,7-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one; 6-Mercapto-1-(4-fluorobenzyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one; 1-(4-Fluorobenzyl)-6-thioxo-1,4,5,6-tetrahydropyrazolo[3,4-d]pyrimidin-4-one; 1204298-15-6; 1-(4-Fluorobenzyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one; CAS 1204298-15-6
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorobenzyl)-6-Mercapto-1,5-Dihydro-4H-Pyrazolo[3,4-D]Pyrimidin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are available for every shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.