Description

3-(3-Fluorophenyl)Azetidine is a high-value, nitrogen-containing heterocyclic building block of significant interest in modern synthetic chemistry. Its core value lies in its unique azetidine scaffold functionalized with a fluorinated aromatic ring, making it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where its structure can impart desirable metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) targets, kinase inhibitors, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine atom and rigid azetidine ring can enhance biological activity and environmental persistence.
• Material Science Research: Serves as a building block for advanced polymers, liquid crystals, and organic electronic materials due to its conformational constraint and potential for further functionalization.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of molecular probes, enzyme inhibitors, and bioconjugation reagents.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-(3-Fluorophenyl)Azetidine
CAS No.	1203798-80-4
Molecular Formula	C9H10FN
Molecular Weight	151.18 g/mol
Synonyms	3-(3-Fluorophenyl)azetidine; Azetidine, 3-(3-fluorophenyl)-; 3-(3-Fluorophenyl)azacyclobutane; 3-Fluoro-3-phenylazetidine; 1-Azetidin-3-yl-3-fluorobenzene; 3-(m-Fluorophenyl)azetidine; 1203798-80-4; m-Fluorophenylazetidine
EINECS	Contact for details

Quality Control

Our 3-(3-Fluorophenyl)Azetidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and development under cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.