Description

2-Methoxy-4-Trifluoromethyl-5-Pyrimidinecarboxylic Acid is a high-value pyrimidine derivative, a key building block in modern synthetic chemistry. Its trifluoromethyl and carboxylic acid functionalities make it a versatile intermediate for creating complex molecules with enhanced biological activity and physicochemical properties. This compound is primarily sought after by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, including potential drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve metabolic stability and lipophilicity.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or linker in the design of chemical probes and enzyme inhibitors for biological research.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up manufacturing for clients in the life sciences sector.

Basic Information

Product Name	2-Methoxy-4-Trifluoromethyl-5-Pyrimidinecarboxylic Acid
CAS No.	1202980-50-4
Molecular Formula	C7H5F3N2O3
Molecular Weight	222.12 g/mol
Synonyms	5-Pyrimidinecarboxylic acid, 2-methoxy-4-(trifluoromethyl)-; 2-Methoxy-4-(trifluoromethyl)pyrimidine-5-carboxylic acid; 4-(Trifluoromethyl)-2-methoxypyrimidine-5-carboxylic acid; 2-Methoxy-4-trifluoromethylpyrimidine-5-carboxylic acid; 1202980-50-4; 2-Methoxy-4-CF3-5-pyrimidinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Methoxy-4-Trifluoromethyl-5-Pyrimidinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP standards where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and returned to storage immediately after use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.