Description

2-Chloro-4-(Morpholin-4-Yl)-7H-Pyrrolo[2,3-D]Pyrimidine is a high-value heterocyclic building block and pharmaceutical intermediate of significant interest in modern medicinal chemistry. Its core pyrrolopyrimidine scaffold, functionalized with a morpholine ring and a chloro substituent, makes it a versatile precursor for the synthesis of targeted kinase inhibitors and other bioactive molecules. This compound is essential for research and development laboratories and production facilities in the pharmaceutical and biotechnology sectors seeking to develop novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of small-molecule drugs, particularly protein kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biochemical Tool Compound: Serves as a starting material or reference standard for the synthesis of probes used in biochemical and cellular assays.
• API Synthesis: Employed in the multi-step synthesis of Active Pharmaceutical Ingredients (APIs) targeting specific enzymatic pathways.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs engaged in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and chemical biology.

Basic Information

Product Name	2-Chloro-4-(Morpholin-4-Yl)-7H-Pyrrolo[2,3-D]Pyrimidine
CAS No.	1202885-72-0
Molecular Formula	C10H11ClN4O
Molecular Weight	238.67 g/mol
Synonyms	2-Chloro-4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine, 2-chloro-4-(4-morpholinyl)-; 2-Chloro-4-morpholinopyrrolo[2,3-d]pyrimidine; 4-(2-Chloropyrrolo[2,3-d]pyrimidin-4-yl)morpholine; 1202885-72-0; 2-Chloro-4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidine; 2-Chloro-4-(4-morpholinyl)-7H-pyrrolo[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(Morpholin-4-Yl)-7H-Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.