Description

tert-Butyl 5-Bromo-4-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine-7-Carboxylate is a high-purity, multi-functional heterocyclic building block of significant importance in modern synthetic chemistry. Its core value lies in its role as a versatile intermediate for constructing complex molecular architectures, particularly in the development of targeted therapeutics. This compound is essential for research and production teams in the pharmaceutical and agrochemical industries, where it serves as a key precursor for kinase inhibitors and other biologically active molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel kinase inhibitors and other small-molecule drug candidates targeting various diseases.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its halogenated pyrrolopyrimidine core.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or probe in the study of protein function and biological pathways.
• Organic Synthesis: Serves as a versatile substrate for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and further functionalization due to its reactive bromo and chloro substituents.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and ligands for catalytic systems.

Basic Information

Product Name	tert-Butyl 5-Bromo-4-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine-7-Carboxylate
CAS No.	1202864-54-7
Molecular Formula	C11H11BrClN3O2
Molecular Weight	332.58 g/mol
Synonyms	5-Bromo-4-chloro-7-[(2-methylpropan-2-yl)oxycarbonyl]-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine-7-carboxylic acid, 5-bromo-4-chloro-, 1,1-dimethylethyl ester; tert-Butyl 5-bromo-4-chloropyrrolo[2,3-d]pyrimidine-7-carboxylate; 5-Bromo-4-chloro-7-(tert-butoxycarbonyl)-7H-pyrrolo[2,3-d]pyrimidine; Boc-5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 5-Bromo-4-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine-7-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced pharmaceutical intermediates. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to store the material under an inert atmosphere or in a desiccator for long-term preservation. Recommended storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Purity (HPLC Area %)	≥97.0%
Single Maximum Impurity	≤1.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.