Description

4-(1-(2-Amino-5-Chloropyrimidin-4-Yl)-2-(Thiaol-2-Yl)But-30-Yn-2-Ol CAS NO 1202764-53-1 is a sophisticated heterocyclic organic compound featuring a pyrimidine core integrated with a thiazole moiety and an alkyne functional group. This unique molecular architecture makes it a high-value intermediate for the synthesis of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily required by research institutions and industrial R&D departments focused on developing next-generation therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel kinase inhibitors, antiviral agents, and other targeted small-molecule drugs.
• Agrochemical Research: Used in developing advanced fungicides and herbicides with novel modes of action.
• Chemical Biology: Serves as a versatile scaffold for probe and ligand discovery in biochemical assays due to its functional group diversity.
• Material Science: Potential precursor for specialty polymers and advanced organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for clients.

Basic Information

Product Name	4-(1-(2-Amino-5-Chloropyrimidin-4-Yl)-2-(Thiaol-2-Yl)But-30-Yn-2-Ol
CAS No.	1202764-53-1
Molecular Formula	C13H11ClN4OS
Molecular Weight	306.77 g/mol
Synonyms	4-(1-(2-Amino-5-chloropyrimidin-4-yl)-2-(thiazol-2-yl)but-3-yn-2-ol; 2-Amino-4-(2-hydroxy-2-(thiazol-2-yl)but-3-yn-1-yl)-5-chloropyrimidine; 5-Chloro-2-amino-4-[2-hydroxy-2-(2-thiazolyl)-3-butynyl]pyrimidine; 1202764-53-1; But-3-yn-2-ol, 1-(2-amino-5-chloro-4-pyrimidinyl)-2-(2-thiazolyl)-; 1-(2-Amino-5-chloro-4-pyrimidinyl)-2-(2-thiazolyl)-3-butyn-2-ol
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request. We adhere to a cGMP-compliant quality management system to ensure traceability and consistency for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.