Description

N4-(3-Aminophenyl)-5-Fluoro-N2-(4-(2-Methoxyethoxy)Phenyl)Pyrimidine-2,4-Diamine is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of targeted therapeutic agents. This compound is critical for research and development in medicinal chemistry, offering a precise building block for creating novel drug candidates. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel kinase inhibitors and other targeted small-molecule drugs.
• Oncology Research: Used in the development and preclinical testing of potential anti-cancer therapeutics.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Employed in route scouting and scale-up studies for active pharmaceutical ingredient (API) manufacturing.
• Biochemical Research: Used as a reference standard or probe in enzymatic and cellular assays.
• Custom Synthesis: Starting material for the contract manufacturing of specialized compounds for clinical trials.

Basic Information

Product Name	N4-(3-Aminophenyl)-5-Fluoro-N2-(4-(2-Methoxyethoxy)Phenyl)Pyrimidine-2,4-Diamine
CAS No.	1202759-91-8
Molecular Formula	C19H20FN5O2
Molecular Weight	369.40 g/mol
Synonyms	5-Fluoro-N2-[4-(2-methoxyethoxy)phenyl]-N4-(3-aminophenyl)pyrimidine-2,4-diamine; 1202759-91-8; UNII-9C3L8T84Q2; 9C3L8T84Q2; 5-Fluoro-N2-(4-(2-methoxyethoxy)phenyl)-N4-(3-aminophenyl)-2,4-pyrimidinediamine; N4-(3-Aminophenyl)-5-fluoro-N2-[4-(2-methoxyethoxy)phenyl]pyrimidine-2,4-diamine; BDBM50164957; AOB67707
EINECS	Contact for details

Quality Control

Our N4-(3-Aminophenyl)-5-Fluoro-N2-(4-(2-Methoxyethoxy)Phenyl)Pyrimidine-2,4-Diamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a dry, well-ventilated area. This material is light-sensitive and easily oxidized; prolonged exposure to air, light, or moisture should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.