Description

2-Chloro-5-Methyl-n-(3-Nitrophenyl)Pyrimidin-4-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyrimidine core functionalized with chloro, methyl, and nitrophenyl groups. This compound matters for its critical role as a versatile building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in oncology and antiviral research. It is primarily needed by R&D laboratories, process development chemists, and manufacturers in the pharmaceutical and agrochemical sectors seeking reliable, high-quality intermediates for scale-up and production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its heterocyclic structure for biological activity.
• Chemical Synthesis Building Block: Serves as a versatile scaffold for further functionalization in medicinal chemistry and material science.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) settings for exploratory research and method development.
• Process Chemistry & Scale-Up: Integral for optimizing synthetic routes and scaling production from laboratory to pilot plant and commercial manufacturing.

Basic Information

Product Name	2-Chloro-5-Methyl-n-(3-Nitrophenyl)Pyrimidin-4-Amine
CAS No.	1202759-74-7
Molecular Formula	C11H9ClN4O2
Molecular Weight	264.67 g/mol
Synonyms	4-Amino-2-chloro-5-methyl-N-(3-nitrophenyl)pyrimidine; 2-Chloro-5-methyl-N-(3-nitrophenyl)pyrimidin-4-amine; 2-Chloro-5-methyl-4-[(3-nitrophenyl)amino]pyrimidine; 1202759-74-7; 4-Pyrimidinamine, 2-chloro-5-methyl-N-(3-nitrophenyl)-; N-(3-Nitrophenyl)-2-chloro-5-methylpyrimidin-4-amine
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Methyl-n-(3-Nitrophenyl)Pyrimidin-4-Amine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.