Description

2-(1,3-Dimethyl-2,4-Dioxo-1,2,3,4-Tetrahydroquinazolin-5-Yl)Acetic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct quinazoline-dione core structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic frameworks. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug molecules, especially kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides that leverage the quinazoline scaffold for bioactivity.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or host materials in OLED displays due to its rigid, conjugated structure.
• Biochemical Research: Employed as a standard or reagent in biochemical assays and proteomics research to study enzyme interactions.
• Fine Chemical Production: Utilized in custom synthesis and contract manufacturing for producing complex, high-value specialty chemicals.
• Academic & Industrial R&D: A valuable compound for medicinal chemistry programs and material science research in both academic and corporate laboratories.

Basic Information

Product Name	2-(1,3-Dimethyl-2,4-Dioxo-1,2,3,4-Tetrahydroquinazolin-5-Yl)Acetic Acid
CAS No.	1202679-03-5
Molecular Formula	C₁₂H₁₂N₂O₄
Molecular Weight	248.24 g/mol
Synonyms	5-Carboxymethyl-1,3-dimethylquinazoline-2,4(1H,3H)-dione; 1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-5-acetic acid; Quinazoline-2,4-dione-5-acetic acid derivative; 5-Acetic acid-1,3-dimethylquinazoline-2,4-dione; DMDTQA; CAS 1202679-03-5
EINECS	Contact for details

Quality Control

Our 2-(1,3-Dimethyl-2,4-Dioxo-1,2,3,4-Tetrahydroquinazolin-5-Yl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.